Topical Antibiotics Examples, Learn about when you might need one and possible side effects. View important safety information, ratings, user reviews, popularity and more. Common antibiotics include dicloxacillin, erythromycin, and tetracycline. In addition, We would like to show you a description here but the site won’t allow us. But, when it comes to prescribing oral antibiotics, we often hesitate or Eczema - atopic: Topical antibiotics and antiseptics Last revised in March 2025 What do I need to know about prescribing topical antiseptics and antibiotics? Antiseptics are used to lower bacterial load. These antibiotics work by killing the bacteria that cause these skin Discover the essential role of topical antibiotics in dermatology, exploring their uses, benefits, and potential side effects. Topical antibiotics are a popular choice for treating various skin conditions, including acne, rosacea, and impetigo. In most Compare topical antibiotics. Compare the many treatment options and their uses. Topical corticosteroids are an essential tool for treating inflammatory skin conditions such as psoriasis and atopic dermatitis. WHAT ARE TOPICAL SULFONAMIDES AND HOW DO THEY WORK? Topical sulfonamides (also called sulfa drugs) are a group of synthetic medicines that contain sulfanilamide (a sulfur-containing Drug Safety Update May 2024: Topical steroids: introduction of new labelling and a reminder of the possibility of severe side effects, including Topical Steroid Withdrawal Reactions September 2021: We would like to show you a description here but the site won’t allow us. For mild inflammatory acne, antibiotic creams, gels, or wipes Best Antibiotics for Skin Infections Skin infections, such as bacterial infections or wounds, can be effectively treated with topical antibiotics. Topical Topical Antibiotics: These are used to treat bacterial infections. Tetracyclines are a class of antibiotics that healthcare providers prescribe to treat various bacterial infections. They include antibiotics, antibacterial, antifungal and antiviral agents. A topical antifungal medication is a cream, solution, lotion, powder, gel, spray or lacquer applied to the skin surface to treat a fungal infection. Topical Antibiotics. Over-the-counter topical antibiotics and antiseptics may be used to treat minor wounds, including cuts, abrasions and burns. We review the evidence for the major clinical uses of topical antibiotics and antiseptics. Explore without interruption, create a free account. Resistance to antifungals can Acne management Treatment options available for acne include topical therapies (available over the counter or as prescriptions), systemic Examples of such agents include antibacterial, antifungal, and antiparasitic medications. These medicines, including mupirocin or Topical antibiotics treat skin infections, acne, and wounds by targeting bacteria directly on the skin. While clindamycin does come in an oral form to treat acne, it is much Background: Fluoroquinolones, available in topical and oral formulations, are used to manage bacterial skin and soft tissue infections, Bacitracin and Neosporin are both topical antibiotics — medicated creams that a person can use directly on their skin. There Topical antibiotics are drugs that treat infections on the outside of your body. This article reviews the literature Perioral dermatitis is a red, itchy rash around the mouth that may include small red bumps and flaky skin. Learn about effective treatments, topical antibiotics, and skincare tips for infection control. They contain Find detailed information on prescription drugs, OTC medications, vitamins and dietary supplements, including their uses, side effects, and interactions. 5% ointment is commonly used in infants and is also the standard for ophthalmia This review evaluates the use of topical corticosteroid and antimicrobial combinations in treating various skin, eye, ear, and nasal conditions. Antibiotics are medicines that destroy or inhibit the growth of susceptible Polysporin, Neosporin, and bacitracin are all OTC antibiotic ointments to help treat or prevent infection. Topical clindamycin is used to help control acne. However, the rising prevalence of antibiotic-resistant Topical antibiotics for skin infections: when are they appropriate? In the community, many patients have skin and soft tissue infections that are relatively minor, e. Some fungal skin Topical antimicrobial therapy dates to ancient times when a wide variety of substances such as grease, lint oil, wine, and metallic salts were applied to wounds. Checking your browser before accessing pmc. Discover the top seven antibiotics for treating skin infections effectively. In selecting an antibiotic to treat a person Plenty of products, like echinacea and garlic, may have natural antibiotic qualities. Gastrointestinal side effects are common. These are usually caused by a bacteria called Topical Antibiotics Clindamycin is most widely prescribed as a topical antibiotic. We've rounded up a list of the most common antibiotics. Conclusion This comparison of antibiotic ointments can help select the best treatment for your patient. Two forms of What are the best antibiotic tablets for skin infections? Different antibiotic tablets may be more effective against skin infections depending on the Antibacterial resistance of propionibacterium acnes is increasing; there is cross-resistance between erythromycin and clindamycin. Here are some general guidelines for choosing and using topical nonprescription Learn about Over The Counter Antibiotics, their uses, benefits, and limitations, how to use them, & when to seek We would like to show you a description here but the site won’t allow us. Antibiotics for Topical Use: Overview You'll soon need a free account to access DrugBank. And many of these topical products are available over Purpose Topical antibiotics help prevent infections caused by bacteria that get into minor cuts, scrapes, and burns. Link to DermNet's pages about skin creams, lotions, ointments, solutions and potions. Learn about the different topical antibiotic creams and ointments. Antiseptics help prevent infection by killing or slowing germs on your skin — just don’t confuse them with disinfectants. Antibiotics vs. Topical antibiotics Antiseptics are chemical agents that slow or stop the growth of micro-organisms on external body surfaces, helping prevent infections. Our Topical steroids with anti-infectives What are Topical steroids with anti-infectives? Topical steroids with anti-infectives are combination creams, ointments, gels, shampoos, or powders that contain both a Due to the widespread use of topical antibiotics and their importance in dermatology, a literature review was performed using a systematic search of Potential Interactions with Other Medications Antibacterial creams can interact with other medications, including other topical creams and oral antibiotics. They are Topical antibiotic therapy is a central component of patient management for several skin conditions, including acne, hidradenitis suppurativa, rosacea, impetigo or other superinfected The effect of low-dose doxycycline in other skin disorders is unknown and it is quite common for an antibiotic dose to be prescribed. To avoid development of resistance: when possible use non-antibiotic What are examples of topical antibiotics? Some widely used topical antibiotics are bacitracin, neomycin, mupirocin, and polymyxin B. . gov 1. Review key antibiotics in the optometrist's toolkit for treating and managing ocular disease and use the downloadable cheat sheet for quick reference. Topical antibiotics1 applied to the skin – usually cause more harm than good There are very few evidence-based reasons to apply antibiotic creams or ointments to the skin. Topical antibiotic creams are medications designed to treat bacterial infections on the skin's surface. Topical (skin) creams, ointments, gels and sprays. Topical acne agents are creams, gels, lotions, and washes that are used on the skin and contain ingredients that treat acne. scrapes and scratches or mild folliculitis. For certain types of skin wounds, you may need prescription topical antibiotics, such as mupirocin (Centany) or metronidazole (Metrogel). For instance, some authors suggest using topical antibiotics in addition to systemic therapy, despite the literature not demonstrating a clinical advantage, whereas other sources caution We would like to show you a description here but the site won’t allow us. Vaginal suppositories. The corticosteroid component is Adjunctive Medical Therapy Clinicians have used an assortment of agents in conjunction with oral antibiotics for the treatment of both acute and chronic sinusitis in children, including nasal saline Antibiotics are commonly used to treat acne. Common agents include mupirocin, neomycin, and polymyxin B. They are available both over-the-counter and with a prescription. Also, the use of topical antibiotics Treat common fungal infections with the right antifungal cream. Treatment options include stopping The most common application of topical antibiotics for active infection in the pediatric patient is probably for use in the therapy of impetigo. Aciclovir Acne treatment Learn about the different types of antibiotics available and their roles in treating infections. , mupirocin [Bactroban], retapamulin [Altabax]) are options in patients with impetigo and folliculitis (Table 5). Topical antibiotics play an important role in the management of many common dermatologic conditions (Table 218-1). Minor furunculosis, folliculitis and small abscesses without cellulitis do not need antibiotic treatment Topical antibiotics are not usually appropriate Antibiotics can effectively kill acne-causing bacteria and reduce inflammation Topical antibiotics are typically prescribed for mild-to-moderate acne Provides information on topical agents and dressings for local burn wound care, including their types, uses, and effectiveness. Application is usually once or twice a day and Commonly available topical antibiotics include bacitracin, neomycin, and polymyxin B, often found in over-the-counter products, sometimes in combination for broader coverage. A variety of topical antibiotics are available such as bacitracin, mupirocin, gramicidin, fusidic acid and gentamycin. When to use topical antibiotics According to current recommendations, topical mupirocin is only recommended in cases of mild impetigo and folliculitis. Also, the use of topical antibiotics Topical petrolatum is as effective as these topical antibiotics and does not cause contact dermatitis, which these antibiotics, especially topical neomycin, can cause. Both antiseptics and antibiotics can Topical antifungals and topical corticosteroids Avoid combination antifungal and corticosteroid topical medications. Available 24/7 in all 50 states! Topical antibiotics can help heal minor wounds, but are they always the best choice? Learn when to use them, when to skip them, and which ones work best. Learn how they work, when to use them, and what to watch out for. Topical corticosteroids are classified by strength and the risk of Topical antibiotics are available in over-the-counter (OTC) creams and ointments. Mupirocin, for example, is widely used to treat impetigo and Description Clindamycin belongs to the family of medicines called antibiotics. If the wounds are left untreated, Topical antibiotics may negate the need for systemic antibiotics in the treatment of impetigo; they are unnecessary as postsurgical prophylaxis to prevent wound infection. Topical antibiotics, including clindamycin 1% and erythromycin 2%, are commonly used for the treatment of mild to moderate acne When properly employed, topical antibiotic therapy should be part of a comprehensive treatment program, potentially including debridement, source control, evaluation for comorbidities, and An antibiotic is a type of antimicrobial substance active against bacteria. In this review, we discuss specific challenges of treating wound infections and the advances in drug delivery platforms and formulations that are under development Topical antibiotics are commonly used to treat minor skin injuries, such as cuts, scrapes, and burns. For minor infections and impetigo only and where Emulsiderm ® will not suffice, topical sodium fusidate 2% ointment can be Topical Antiseptic Products: Hand Sanitizers and Antibacterial Soaps FDA is undertaking a review of active ingredients used in a variety of over-the-counter Topical antibiotics are used to treat a variety of skin infections caused by bacteria, such as impetigo, folliculitis, and cellulitis. What are the best topical antimicrobials products in 2026? We analyzed 4,606 topical antimicrobials reviews to do the research for you. If the wounds are left untreated, Identify the most effective antibiotic cream for your skin infection from our expert-curated list of 12 top performers. Because When used for the ‘blind’ therapy of undiagnosed serious infections it is usually given in conjunction with a penicillin or metronidazole (or both). They kill bacteria or We would like to show you a description here but the site won’t allow us. nih. 3% antibiotic solution provides approximately 3000 μg/mL concentration at the application site 1 The vehicle (cream base) typically consists of water, alcohols, petrolatum, Impetigo requires topical antiseptic/antibacterial or systemic antibacterial treatment, see Skin infections, antibacterial therapy. They work by killing or inhibiting the growth of bacteria, providing relief for minor cuts, burns, and POLYSPORIN® vs NEOSPORIN® vs Bacitracin: Key Differences In Ointments Antibiotic ointments are used to fight bacterial infections. This guide explains which ones are over-the-counter (OTC) and which require a prescription, and how to use them safely. What is the clinical effectiveness of topical antibiotics for patients with infected dermatitis? The main findings and conclusions of the included SRs and RCTs Topical antibiotics are used for various purposes in dermatology. gov Compare risks and benefits of common medications used for Skin or Soft Tissue Infection. They Key Differences Between Topical Antibiotics and Oral Antibiotics When deciding between topical and oral antibiotics for treating a skin infection, the key factors to consider are how the When treating ocular surface infections, optometrists typically feel comfortable with the use of topical antibiotics. TOPICAL ANTIBIOTICS AND OR SULPHONAMIDS These medications are applied directly onto the skin for the treatment of bacterial skin infections such as impetigo (red sores), recurring boils, etc. Summary of Findings Question 1. Find out how. Some Topical antibiotics assist in preventing infections caused by bacteria. There are numerous products available in When caring for a cut or other wound, it might seem logical to apply an antibiotic cream or ointment from the store to fight off germs and prevent infection. Antibiotics. Explore the differences between systemic antibiotics and topical antimicrobials, and when to use each for effective treatment. Antibiotics are medications that treat bacterial infections. All other infections should be managed Possible choices include a topical retinoid and a topical antibiotic, or a retinoid and the benzoyl peroxide–erythromycin combination. Keep reading to learn more about the different types of topical antibiotics, what they are most commonly used for, and There are several types of topical antibiotics available, including clindamycin, erythromycin, and tetracycline. nlm. They work by killing or stopping the growth of bacteria right where the This resource provides a clinical guide on topical antibiotics and antifungals for healthcare professionals. Made with polymyxin, bacitracin, and neomycin, this first aid ointment helps protect minor wounds. We would like to show you a description here but the site won’t allow us. These ointments help prevent bacterial Summary of antimicrobial prescribing guidance – managing common infections For all PHE guidance, follow PHE’s principles of treatment. Comprehensive guide on treatment options for acute cellulitis and erysipelas in adults, including management strategies and antibiotic recommendations. gov Topical antibiotics inhibit or destroy the growth of bacteria. Generic list of "Topical Antibiotic preparations" Gentamicin Sulfate (Topical) Indicated for Burn, Eczema, Seborrhetic dermatitis, Ecthyma, Excoriation, Folliculitis, Furunculosis, Insect bites and stings, These antibiotic ointments, topical antifungal agents, and topical medications used for burns are indicated for the surface of the skin, as opposed Topical antibiotics help prevent infections caused by bacteria that get into minor cuts, scrapes, and burns. In addition, we review the mechanisms of action of common topical agents and define the clinical and molecular Compare topical antibiotics for Bacterial Skin Infection. Sulfonamide allergies can manifest in several different ways, for Antifungal medication is used to treat fungal infections of the skin, scalp and nails. Uses include prophylaxis of infection for burns, traumatic wounds, and intravascular Coupled with the antibacterial action of the antibiotic ingredient, topical antibiotic ointments provide a safe and effective option in wound healing. They are typically used for mild acne, Overview What are prescription topical treatments? Topical treatments, or “topicals,” for eczema are medications, including creams, gels and foams, that are applied to the skin to manage A topical retinoid combined with a topical antibiotic is another option. Explore expert insights and find the right solutions for healthier skin. Macrolides are a group of antibiotics that treat bacterial infections. How long do you need to take antifungal drugs? Treatment length varies depending on the fungal infection. Eye drops are instilled directly into the Topical antibiotics licenced in the UK for treatment of acne vulgaris include clindamycin and erythromycin. More severe reactions may require topical or oral steroids and possibly hospital admission. This potency gives topicals the strength to obliterate the targeted Medications used to treat skin conditions include topical and oral drugs. For example creams, ointment and lotions are applied topically on the skin. If the wounds are left untreated, Here are Money’s picks for the best topical antibiotics and antiseptics, along with data on their active ingredients and general notes about their efficacy Antibiotics treat certain bacterial infections, not viruses like cold or flu. What are some of the most commonly prescribed antibiotics? View our list of the top generic and brand drugs and learn about the types of antibiotics. In addition, we review the mechanisms of action of common topical What are topical antibiotics and how do they work? Topical antibiotics are medicines applied directly to the skin to treat infections. Learn more about what these drugs can do and how to use them. gov We would like to show you a description here but the site won’t allow us. These are the most effective options. Discover the best antibiotics to treat infections in wounds and learn how to properly care for and prevent infection in a wound. For restrictions and Topical medications for skin conditions Created 2003. gov For example, if neomycin is thought to have caused a sensitivity reaction, all preparations containing aminoglycosides should be avoided. These antibiotics come in various forms, such as creams, gels, and Topical antibacterials are antimicrobial agents used externally on the skin, eyes, or mucous surfaces to inhibit bacterial growth or kill bacteria at the site Over-the-counter topical antibiotic products often include medications like bacitracin, neomycin or polymyxin B. A topical foam formulation of Antibiotics are a safe and effective treatment for a type of acne called inflammatory acne. Creams, tablets, pessaries, and shampoos are the most common What are some common antibiotics that a doctor may prescribe? Read on to learn more about the different classes of antibiotics and how they work. If the wounds are left Checking your browser before accessing pmc. However, topical Labelling Standard Category: Topical Antibiotics For First Aid Use Definition First aid antibiotic: an antibiotic-containing drug product, suitable for self-medication, which is applied topically to the skin to 1: Topical antibiotics like clindamycin and erythromycin work best when used with benzoyl peroxide. Mupirocin ointment uses, Discover Neosporin® Original Triple Antibiotic Ointment. Many antifungal medications are suitable for both Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, and sold under the brand name Neosporin, among others, is an antibiotic medication used Action and Uses Topical preparations for the skin may include medicated bar soaps and foams, sulfur preparations, topical antibiotics, and We would like to show you a description here but the site won’t allow us. Learn how to choose the best option for athlete's foot, jock itch, and more. What’s the difference between them and which Antibiotics, topical Definition Topical antibiotics are medicines applied to the skin to kill bacteria. Topical Introduction Topical treatment for acne is available as washes, solutions, lotions, gels and creams. gov For example, a 0. Mupirocin Oral or topical antibiotics — such as tetracycline and erythromycin — can help treat severe, painful acne that is related to bacteria on the skin. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the Most patches contain time-release mechanisms that allow the skin to absorb small amounts of medication over the course of several hours or days. They may have a single or multiple active ingredients. It may be used alone or with one or more other medicines Topical antibiotics play a crucial role in managing various dermatological conditions, offering targeted therapy with minimal systemic absorption. 5, 27 Beta-lactams Topical petrolatum is as effective as these topical antibiotics and does not cause contact dermatitis, which these antibiotics, especially topical neomycin, can cause. Introduction Topical antibiotics play a key role in dermatology and have several uses, including mild-to-moderate acne vulgaris, secondarily infected Topical antibiotics are antibiotics that have been manufactured into a cream or an ointment and can be applied directly to the skin. Gentamicin is used together with another antibiotic for the Topical antibacterial agents offer a useful alternative to systemic agents in certain circumstances. 2: Topical antibiotics for acne can cause dryness and Topical agents are used locally, where the medicine is applied on the area being treated. Topical antimicrobials are medications used to treat skin infections caused by bacteria and reduce the redness, swelling, itching, and discomfort of various skin conditions. Some sulfonamides are applied directly to the skin (topically) to treat burns and Fortunately, nearly all topical ophthalmic antibiotics are broad spectrum, and so meet the needs of the marketplace. Creams, gels and sprays can help relieve the pain from osteoarthritis. Antibiotics are a common and important type of medicine that treats bacterial infections. Learn about 11 natural antibiotics, including honey and garlic, that may aid in fighting infections. Core data resources will remain freely available. They are available as topical preparations for mild acne, and as tablets, capsules and elixirs for oral use in If your dog has a wound, clean it with a pet-safe antiseptic solution and seek professional advice before applying any topical treatment. When selecting an antibiotic ointment for the Mupirocin ointment is an antibiotic ointment used to treat bacterial skin infections, including staph or strep infections. They are also used for prophylaxis of We would like to show you a description here but the site won’t allow us. WebMD tells you what is available on your drugstore shelves - and your own freezer - to alleviate pain. For example, using multiple topical What is Antibiotic creams used to treat? Skin infections caused by bacteria; for example impetigo, infected hair follicles (folliculitis), infected eczema. S. Each antibiotic is effective only against certain types of bacteria. Among the products that contain one or more of these ingredients are Get antibiotics prescribed online - manage bacterial infections with a virtual doctor visit for quick diagnosis & treatment. Antiseptic Cream vs Antibiotic Cream Antiseptic creams and antibiotic The topical route offers several advantages, including the avoidance of systemic toxicity and side effects, the decreased induction of bacterial resistance, and the high concentration of antibacterial agent at Some fungal infections that affect the skin can be treated with topical medications like creams. As resistance is increasing reserve topical antibiotics for very localised lesions. Discover the best antibiotic creams for skin infections. These range from antiseptics to antibiotics and newer biological For example, cystic acne can be treated with a combination of both topical and oral antibiotics. Some common topical treatments for skin conditions are: Antibacterials. The purpose of this report is to retrieve and review the existing clinical effectiveness evidence on the treatment of patients with impetigo with the topical Checking your browser before accessing pmc. Read about how to use antibiotics and about when not to use antibiotics. Antibiotic creams are another prescription treatment option. Antibiotics target the bacterial infection that underlies many acne outbreaks and can treat inflamed skin and red, painful pimples. Although many antibacterial drugs are available in topical preparations, some This treatment summary topic describes quinolones The MHRA and CHM have released important safety information regarding the use of systemic and inhaled fluoroquinolones. Topical antibiotics help prevent infections caused by bacteria that get into minor cuts, scrapes, and burns. Treating minor wounds with antibiotics allows quicker healing. Different kinds of topical antibiotics kill different types of bacteria. Used properly, antibiotics can save lives by fighting bacterial infections. Anti-infective Agents. These Topical application has many potential advantages over systemic therapy that includes high and sustained concentrations of drug directly at the infected site, low quantity of antibiotic needed, Find out about antifungal medicines, which are used to treat fungal infections such as thrush and athlete's foot. If two products are used separately, they should be applied 12 hours apart (for example topical retinoid at night and topical Topical antibiotics for skin infections: should they be prescribed at all? Clinical indications for the use of topical antibiotics are continuing to narrow, driven by increasing resistance rates in New Zealand. But medical providers often recommend using petroleum jelly (formally We surveyed 134 dermatologists to rank the best topical antibiotic and antiseptic products to treat minor wounds. Topical antibiotic therapy is a central component of patient management for several skin conditions, including acne, hidradenitis suppurativa, rosacea, impetigo or other superinfected dermatitis, and Decreased systemic toxicity, ease of application, and increased concentrations at the target site are some of the important advantages topical antibacterial agents offer. Check out their top picks at U. I always tell my patients that consistency is key with We review the evidence for the major clinical uses of topical antibiotics and antiseptics. antiseptics Antibiotics are a type of prescription medication that can treat bacterial infections. 10 Topical antimicrobials and antiseptics A number of topical agents have been used over the years for the treatment of pressure ulcers. Some of the most common uses include treatment of acne, treatment and prevention of wound infection (s), impetigo or impetiginized Yes, many topical antibiotics are available for skin infections. ncbi. The acne products that are best for you depends on your skin type, acne type and skin care preferences. Oral antibiotics are used to treat many skin conditions. Common examples include birth Topical Antibiotics Keep minor injuries minor with our topical ointments and creams that help prevent infection so wounds can heal quickly and properly. Compare topical antibiotics for Acne. Face it: a drug having only This article provides an 42 common antibiotics, detailing their classifications, uses, mechanisms, and activity spectrums for easy reference. There are many different types which are appropriate in specific medical contexts. It is intended to aid selection of an appropriate antibiotic for typical patients Topical compounded prescriptions have well over one thousand times the strength of oral medications when they are applied locally. Since then, topical Antibiotics are effective for treating a wound infection and there are various types you can use, including topical, oral, and Topical antibiotics (e. Checking your browser before accessing pubmed. Learn tips for safe antibiotic use that can protect you and all of us. Topical corticosteroids are used for the treatment of inflammatory conditions of the skin (other than those arising from an infection), in particular eczema, contact dermatitis, insect stings, and eczema of Topical antibiotics play a key role in dermatology and have several uses, including mild-to-moderate acne vulgaris, secondarily infected dermatitis, rosacea, treatment and prevention of wound Preferred list (P) FUSIDIC ACID 2% cream There is a high risk of fusidic acid resistance. Find the most popular drugs, view ratings and user reviews. However, these antibiotic creams and ointments Which topical antibiotics are safe for infants and young children? Erythromycin 0. Azelaic acid reduces inflammation and can improve skin discoloration after acne heals. gov bpac nz Primary Care Antibiotic Guide Antibiotics: choices for common infections The following information is a guide. g. b. (1) Types of topical antibacterial agents include bacitracin ointment, bacitracin-Neomycin Checking your browser before accessing pmc. Short term use during bacterial skin infection only. Prescription topical acne treatments can be more effective than over-the-counter options. Description Some topical antibiotics are available without a prescription and are sold in What are Topical anti-infectives? Topical anti-infective agents act by either killing or inhibiting the spread of the infectious agent. But using them safely and effectively is important. [Rosenfeld, 2014; Antifungal resistance is a subset of antimicrobial resistance, that specifically applies to fungi that have become resistant to antifungals. They are prescribed most often by dermatologists for the management of mild-to Sulfonamides are a class of antibiotics that are effective against many gram-positive bacteria and gram-negative bacteria. Many first-aid antibiotic products contain combinations of antibiotics to make them effective against a broad range of bacteria.
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